Artery was originally a music venue that was a front for a criminal vampire gang in the 1970s. After being badly damaged in a decisive raid by the officers of Precinct 13 backed up by AEON agents, the club was shuttered and remained vacant until the early 90s. It was purchased by the vampire impresario Vincent Brama, refurbished, and opened as a mostly-legit high-end gothic-chic dance club.
In the year 2000, with Vincent running feral in the sewers, Grizelda Alletante, once hostess and assistant to Vincent, briefly ran the club. By late spring of that year, Vincent had recovered and was running the club again.